Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3014
Gene Symbol: H2AX
H2AX 		0.070 PosttranslationalModification disease BEFREE γ-H2AX phosphorylation after bleomycin treatment in PBL did not differ between CRC and BC patients. 29052312 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.400 Biomarker disease BEFREE β-Galactoside α-2,6-sialyltransferase 1 (ST6Gal1) catalyzes EGFR sialylation that is associated with gefitinib resistance in colorectal cancers, and this was also investigated. 30187356 2018
Entrez Id: 6480
Gene Symbol: ST6GAL1
ST6GAL1 		0.080 Biomarker disease BEFREE β-Galactoside α-2,6-sialyltransferase 1 (ST6Gal1) catalyzes EGFR sialylation that is associated with gefitinib resistance in colorectal cancers, and this was also investigated. 30187356 2018
Entrez Id: 3661
Gene Symbol: IRF3
IRF3 		0.020 Biomarker disease BEFREE β-catenin regulates IRF3-mediated innate immune signalling in colorectal cancer. 30004146 2018
Entrez Id: 9368
Gene Symbol: SLC9A3R1
SLC9A3R1 		0.080 Biomarker disease BEFREE β-catenin knockdown promotes NHERF1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy. 29551770 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.700 Biomarker disease BEFREE β-Arrestins (Arrb) participate in the regulation of multiple signaling pathways, including Wnt/β-catenin, the major actor in human colorectal cancer initiation. 22315403 2012
Entrez Id: 5562
Gene Symbol: PRKAA1
PRKAA1 		0.080 Biomarker disease BEFREE α-enolase promotes tumorigenesis and metastasis via regulating AMPK/mTOR pathway in colorectal cancer. 27996156 2017
Entrez Id: 5564
Gene Symbol: PRKAB1
PRKAB1 		0.060 Biomarker disease BEFREE α-enolase promotes tumorigenesis and metastasis via regulating AMPK/mTOR pathway in colorectal cancer. 27996156 2017
Entrez Id: 5563
Gene Symbol: PRKAA2
PRKAA2 		0.060 Biomarker disease BEFREE α-enolase promotes tumorigenesis and metastasis via regulating AMPK/mTOR pathway in colorectal cancer. 27996156 2017
Entrez Id: 6422
Gene Symbol: SFRP1
SFRP1 		0.400 Biomarker disease CTD_human [The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor]. 17923031 2007
Entrez Id: 6423
Gene Symbol: SFRP2
SFRP2 		0.400 Biomarker disease CTD_human [The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor]. 17923031 2007
Entrez Id: 6424
Gene Symbol: SFRP4
SFRP4 		0.330 Biomarker disease CTD_human [The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor]. 17923031 2007
Entrez Id: 6425
Gene Symbol: SFRP5
SFRP5 		0.310 Biomarker disease CTD_human [The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor]. 17923031 2007
Entrez Id: 1398
Gene Symbol: CRK
CRK 		0.100 Biomarker disease BEFREE [Corrigendum] Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK‑mediated DR5 regulation in colorectal cancer. 30864690 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		0.100 Biomarker disease BEFREE [Corrigendum] Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK‑mediated DR5 regulation in colorectal cancer. 30864690 2019
Entrez Id: 25897
Gene Symbol: RNF19A
RNF19A 		0.100 Biomarker disease BEFREE [Corrigendum] Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK‑mediated DR5 regulation in colorectal cancer. 30864690 2019
Entrez Id: 26073
Gene Symbol: POLDIP2
POLDIP2 		0.100 Biomarker disease BEFREE [Corrigendum] Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK‑mediated DR5 regulation in colorectal cancer. 30864690 2019
Entrez Id: 9402
Gene Symbol: GRAP2
GRAP2 		0.100 Biomarker disease BEFREE [Corrigendum] Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK‑mediated DR5 regulation in colorectal cancer. 30864690 2019
Entrez Id: 7965
Gene Symbol: AIMP2
AIMP2 		0.100 Biomarker disease BEFREE [Corrigendum] Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK‑mediated DR5 regulation in colorectal cancer. 30864690 2019
Entrez Id: 10598
Gene Symbol: AHSA1
AHSA1 		0.100 Biomarker disease BEFREE [Corrigendum] Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK‑mediated DR5 regulation in colorectal cancer. 30864690 2019
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14 		0.100 Biomarker disease BEFREE [Corrigendum] Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK‑mediated DR5 regulation in colorectal cancer. 30864690 2019
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		0.400 AlteredExpression disease BEFREE [Corrigendum] Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK‑mediated DR5 regulation in colorectal cancer. 30864690 2019
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1 		0.030 Biomarker disease BEFREE [Corrigendum] Knockdown of lncRNA HNF1A-AS1 inhibits oncogenic phenotypes in colorectal carcinoma. 31257539 2019
Entrez Id: 125919
Gene Symbol: ZNF543
ZNF543 		0.010 Biomarker disease BEFREE ZNF397OS and ZNF543 represented the top scoring associated events that were further validated in an independent cohort and exhibited strong correlation with BMI and excellent and statistically significant efficiency in the discrimination of obese from non-obese CRC patients (area under the curve >0.80; p < 0.05). 29717273 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.700 Biomarker disease BEFREE ZNF281 Regulates Cell Proliferation, Migration and Invasion in Colorectal Cancer through Wnt/β-Catenin Signaling. 31112017 2019